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Author Contributions Mahroz Abid: Conceptualization, Formal Analysis, Data curation, Writing review & editing, Visualization

N -myristoyltransferase inhibition induces ER-stress, cell cycle arrest, and apoptosis in cancer cells

Lactobacillus helps repair the intestinal epithelial barrier by upregulating tight junction proteins and reduces colonic inflammation in UC mice by inhibiting the TLR4-NF-B-NLRP3 signaling pathway [42, 43]

IGF1, IGF2 and insulin act primarily through tyrosine-kinase-linked receptorsthe IGF1 receptor (IGF1R) and insulin receptor (IR)

Elevated Energy Expenditure Preclinical findings demonstrate higher energy expenditure and greater fat oxidation in obese models