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One study doesnt lend enough credibility to the advantage of using GLP-1s and estrogen replacement to accelerate weight loss

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Our study identifies a set of agents with specific GLP-1R trafficking profiles and the potential for greater efficacy and tolerability as T2D treatments

GLP-1 receptor agonists are associated with a modest increase in heart rate

Urinary tract infections were also more common in the retatrutide groups (6.8% to 8.1%) than with placebo (4.8%)