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The LC group received 350 mg/kg LC, the TMZ group received 15 mg/kg TMZ, the AP group received 5 mg/kg AP gavage 1 h prior to modeling, and the other groups received saline

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SOLIQUA 100/33 is contraindicated in patients with known serious hypersensitivity to lixisenatide or insulin glargine [see Contraindications (4)]