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1 Introduction 1.1 Literature review methodology This review was conducted by searching PubMed, Scopus, and Google Scholar databases using the keywords Parkinsons disease, -synuclein, dopaminergic neurons, LRRK2, mitochondrial dysfunction, comorbidities, levodopa, and neuroinflammation. Studies published in English between 2000 and 2025 were included

Bulk transfer of fluid in the interstitial compartment of mammary tumors

Figure 4 6.3 Complementary endocrine actions: insulin sensitization, androgen modulation, and ovulatory regulation The clinical and molecular intersections of vitamin D, MI, and melatonin converge on three tightly connected endocrine domains central to the pathophysiology of PCOS: IR, androgen excess, and ovulatory dysfunction

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The mitochondrial permeability transition contributes to acute ethanol-induced apoptosis in rat hepatocytes

Conclusions SIRT1 represents a mechanistically validated target with notable progress in early-stage drug development for MASLD