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Cytosolic Ca 2+ is taken up by a voltage-dependent anion-selective channel and mitochondrial calcium uniporter channels, leading to accumulation of Ca 2+ in the mitochondrial matrix

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Shorter Lifespan Due to the use of different material systems (liquid, dry or colloid), the cycle life is generally lower than that of 18650 batteries, and the performance is not as good as that of cylindrical batteries when discharged at high currents

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