retatrutide clinical trials phase VisualAbstract: reduces body weight by 17.5% in patients with obesity Retatrutide Availability & Timeline |

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Given the importance of NLRP3 inflammasome in the pathogenesis of fibrotic disease, the antifibrotic effects of GLP-1R could partially be attributed to its inhibitory potential against NLRP3 inflammasome activation

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Retatrutides mechanism of action Retatrutides mechanism of action combines the effects of three hormones naturally produced after eating: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon