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Notably, GLP-1R agonists have been found to modulate gamma-aminobutyric acid (GABA) signaling

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For example, too much iodine can harm thyroid cells and make autoimmune conditions worse

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Therefore, for SLE and LN treatment, adoptive transfer of Tregs can be directly applied, either as polyclonal Tregs or as engineered variants with a receptor of high affinity for the target autoantigen, such as TCR-Tregs or CAR-Tregs, to eliminate or deactivate aberrant immune cells and reduce inflammation in AIDs (75)

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