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As stated above, according to several evidence, acute COVID-19 damage to the CNS may play a central role in the pathogenesis of neuropsychiatric symptoms through several pathophysiological mechanisms: dysregulation of inflammation, astrocytic glial damage, glutamatergic impairment (shift in tryptophan metabolism towards kynurenine pathway, Nf-B, oxidative stress, glutamatergic and excitotoxic damage) and possible glymphatic impairment [15, 46, 82]

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Sima AA: C-peptide and diabetic neuropathy

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Biochemistry 10, 32543263

Mounjaro is indicated for type 2 diabetes (FDA approved May 2022)