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There are multiple potential predisposing/etiologic factors, including cancer itself, treatment-related adverse effects, physiologic complications, impaired performance status, and psychological comorbidities, such as depression [65, 67]

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These functions collectively contribute to the structural and functional integrity of neurons and neuroglia (3, 6, 32)

Instead, doctors will usually perform a physical examination and run a battery of tests to rule out other health problems as potential causes before diagnosing CFS

Still, new or persistent symptoms deserve a medical check to rule out other causes