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Syn-RA16 had a high binding affinity (Kd ~ 24.75 nM), akin to the previously documented RA16 aptamer, and displayed dose-dependent suppression of cell viability, with IC50 values around 118.4 nM

Trends in Biochemical Sciences, 34 (2), 8596

Growth factor and chemokine signaling in tumor angiogenesis A large number of pro-angiogenic factors and their cognate receptors are known to promote vessel formation in tumors, including vascular endothelial growth factor (VEGF), fibroblast growth factor 2 (FGF-2), platelet derived growth factor (PDGF), angiopoietins, ephrins, apelin (APLN) and chemokines

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The quadruple therapy of antibiotics in the treatment of H

2020;33(3):e13379