Other factors especially costs, as well as concerns about long-term safety and side effects, and a preference for other weight-loss tactics have undoubtedly played a role, based on patient surveys
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Reduction of Hyperinsulinaemia and IGF-1 Signalling Elevated circulating insulin and insulin-like growth factor-1 (IGF-1) represent well-established promoters of tumour cell proliferation
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Patients with statin intolerance should first consider evidence-based alternatives like ezetimibe, bempedoic acid, PCSK9 inhibitors, or inclisiran before considering GLP-1 therapy primarily for lipid management
Lifestyle changes might help improve high blood pressure, but many people need to be on medication for it for the rest of their lives and its very similar in weight management, she notes