In addition, a MAGPIX Multiplex Reader was used to measure 25 inflammatory mediators simultaneously in plasma from female [Young ( n = 8), Old Con ( n = 15), and Old mAb ( n = 16)] and male mice [Young ( n = 8), Old Con ( n = 14), and Old mAb ( n = 16)], including: G-CSF, GM-CSF, IFN-, IL-1, IL-1, IL-2, IL-4, IL-5, IL-6, IL-7, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, CXCL-10, CXCL-1, MCP-1, MIP-1, MIP-1, MIP-2, RANTES, and TNF- (MCYTOMAG-70K-PMX
The primary effects don't overlap much, so you're getting additive benefit rather than redundancy
When the iron-binding complexes reach saturation, the excess Fe2 + accumulates in an unstable iron pool
doi: 10.1016/j.psyneuen.2022.105667, 21
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