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Another study noted that MOTS-c improved muscle insulin sensitivity and prevented weight gain in mice fed a high-fat diet

Furthermore, it is noteworthy that in the SELECT trial, a 39.8-month follow-up trial in patients with cardiovascular disease and overweight or obesity, but not diabetes, 46 semaglutide 2.4 mg was superior to placebo in reducing the incidence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke (HR 0.80

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Fisher JN, Peretti GM, Scotti C

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