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Clinical Context Asthma in patients with obesity is often characterized by: More severe symptoms Reduced response to inhaled corticosteroids Increased exacerbation frequency Weight loss has been associated with improved asthma control, but pharmacologic options specifically targeting obesity-related asthma are limited

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Common side effects include: Mild to Moderate Side Effects Nausea Vomiting Diarrhea or constipation Abdominal discomfort Appetite changes Headache Less Common Side Effects: Dizziness Fatigue Injection site reactions Temporary hypoglycemia when combined with other diabetes medications Rare but Serious Side Effects: Pancreatitis: Severe abdominal pain that may radiate to the back Gallbladder disease: Increased risk of gallstones Kidney issues: Worsening kidney function in some patients Thyroid tumors: Observed in animal studies, though human risk is unclear To minimize side effects, we recommend: Important Considerations Before Starting Semaglutide Medical History: Not recommended for individuals with a history of pancreatitis or thyroid cancer

A whopping 18.2% of participants on the 12 mg dose dropped out due to adverse events, while 12.2% of those on the 9 mg dose left early

Treatment-associated weight loss can be significant, which sets this class of medications apart from most other antidiabetic agents

senators sent a letter to the FDA raising concerns over a telehealth companys ad about compounded weight-loss medications