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Current-voltage (IV) relationships were measured by applying voltage steps with a Digidata 1550B with Humsilencer (Axon Instruments) controlled by an IBM-compatible computer with Axon TM pClamp11 TM software (Molecular Devices)

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It is a potent vasodilator, regulating smooth muscle activity, epithelial cell secretion, and blood flow in the gastrointestinal tract

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