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People with type 2 diabetes Both semaglutide and tirzepatide are approved for type 2 diabetes management, and the blood sugar implications of switching are significant

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urease-producing bacteria in the gut increase ammonia production, which contributes to hepatic encephalopathy, and migration of bacteria across the intestinal wall has been implicated in both spontaneous bacterial peritonitis and bleeding due to esophageal varices (Pereg 2011)