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Real-world data associate semaglutide with fewer tobacco-use-disorder encounters than other antidiabetic drugs, though the target-trial-emulation design is observational and has been questioned (Wang et al., 2024a)

Others investigate its impact on cellular repair and hormonal pathways that may impact reproductive tissues

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It applies to both semaglutide and compounded versions

However, the implementation of holistic solutions that consider synergies and trade-offs to target the United Nations' SDGs (181) and simultaneously address health and climate change challenges is restricted by the lack of action by decision-makers at both the national and global levels (189, 193196)