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Nusinersen versus sham control in infantile-onset spinal muscular atrophy

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With Synaptic scaling correlating to homeostatic plasticity, there has been research proving the influence the pathophysiology of several neuropsychiatric and neurological disorders, such as schizophrenia and Alzheimer's disease Metaplasticity varies the threshold level at which plasticity occurs, allowing integrated responses to synaptic activity spaced over time and preventing saturated states of LTP and LTD

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