In the STEP-1 trial, semaglutide 2.4 mg produced a total lean mass loss of 6.92 kg, which represented 13.2% of baseline lean mass
At higher therapeutic doses, you are injecting half a milliliter or more per shot
The honest answer to the question is indirect: semaglutide has been shown to reduce congestion-related symptoms in one specific population studied in a randomized trial, and weight reduction can plausibly ease some forms of dependent lower-limb swelling, but neither of those makes it a treatment for edema
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This higher available dose of semaglutide gives Wegovy a slight advantage over Ozempic when considering its effectiveness
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