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doi: 10.1038/nature22306

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New England Journal of Medicine , 390(8), 712-724

These include: Molecular interactions between receptors Cell signalling pathways Pharmacokinetics Metabolism Human clinical trials under strict control Biomarker reactions Site-specific effects The developments in the field of peptide chemistry might lead to enhanced molecular stability, selectivity for receptors, and analytical techniques

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Presently, BPC 157 therapy has still limited but encouraging clinical evidence (no toxicity in clinical trials (i.e., effective in ulcerative colitis, phase II) and toxicology studies without lethal dose (LD1)), and much more should be further achieved [1,2,3,4,5,6,7,8,9,10,11]