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Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunctions in diet-induced obese mice

AOD-9604's niche is as an adjunct for individuals seeking modest additional fat mobilization with minimal side effects, not as a primary obesity treatment

The only circumstances in which I wouldn't recommend cyanocobalamin is if there is a family history of lebers syndrome (quite a rare hyper-sensitivity to the cyano molecule

Fast forward to more recent clinical interest in NAD+

Form: Capsules

Use of certain medications that may interact with B12 or choline metabolism (e.g., metformin, proton pump inhibitors, or anticholinergic drugs)