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A direct effect of GLP1-RA on immune cells would obviously require that they express the GLP1-R (Glucagon-like peptide-1 receptor) ( Several reports have suggested that GLP1-R signaling may regulate T cell subsets

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Nanotechnology The nanotechnology-based approach is an emerging strategy for the development of therapies targeting tumor angiogenesis which could improve the current pharmacokinetic profiles of anti-angiogenic drugs and favor their selective accumulation in tumors ( in vitro and in vivo assays showed that gold nanoparticle-conjugated quercetin inhibited angiogenesis and invasion of breast cancer by targeting the EGFR/VEGFR-2 signaling pathway ( in vitro and in vivo anti-angiogenic activity in a breast cancer model that was mediated by suppressing VEGF in cancer cells (Shashni et al., 2021)

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This mechanism enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying, which collectively improves glycemic control and promotes weight loss

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