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Mishra AK, van Ruitenbeek AM, Loomans M, Kort HSM

In many cancers, the TME can be manipulated into a tumor-favorable state, preventing immune cells from effectively recognizing and eliminating tumor cells

However, the patient experienced weight gain during this period as an adverse reaction (Figure 2, Table 2, and Appendices C-M)

[DOI] [PubMed] [Google Scholar] 48.Niihara Y, Matsui NM, Shen YM, Akiyama DA, Johnson CS, Sunga MA, Magpayo J, Embury SH, Kalra VK, Ho Cho S, Tanaka KR

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Because piperazine analogues also contain acrylamide, which can bind to GSH, researchers evaluated the chemical and enzymatic binding abilities of multiple piperazine analogues with GSH, as shown in Figure 9 [21]