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However, the significantly greater weight reduction associated with GLP-1 based therapies and their proven health benefits (e.g., reduction in cardiovascular disease with semaglutide [29] and improved sleep apnea with tirzepatide [30]), as well as a wider acceptance that medication is needed for sustained weight reduction success, has triggered a rapid surge in their uptake [31]
(For example, treating sleep apnea can be key for long-term maintenance
This baseline helps you compare when dose increases to 4mg in week 5
It also: Slows stomach emptying Improves insulin secretion Reduces blood sugar spikes When GLP-1 response weakens, appetite increases
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