A major role of the mitochondrial malic enzymes, which includes the NAD(H)-dependent ME2 enzyme, is principally to provide the cell with an alternate source of pyruvate under conditions where glycolytic flux in reduced
[DOI] [PubMed] [Google Scholar] Evans W.J., Morley J.E., Argils J., Bales C., Baracos V., Guttridge D., Jatoi A., Kalantar-Zadeh K., Lochs H., Mantovani G., Marks D., Mitch W.E., Muscaritoli M., Najand A., Ponikowski P., Rossi Fanelli F., Schambelan M., Schols A., Schuster M., Thomas D., Wolfe R., Anker S.D
L-Tyrosine's documented cognitive benefits in research improved working memory, reduced cognitive decline under stress, better sustained attention have been observed at doses of 100-150mg per kilogram of body weight administered acutely in controlled studies
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Assefa, B., Mahmoud, A
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