Boisseau-Garsaud, A
Often referred to as the master antioxidant, glutathione plays a pivotal role in many bodily functions, especially detoxification and cellular protection
Notably, GSH binding motif is not conserved among the other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) justifying their abilities to use wide variety of thiols like cysteine, protein thiols, mercaptoethanol, and dithiothreitol in addition to GSH as reducing equivalent for the catalysis [8, 17, 18]
Chronic oxidative stress in balding scalps accelerates DPC senescence
DHA treatment significantly increases the expression of PPAR in the primary adipocytes of grass carp
Interestingly, a role for UCP2 in the transport of mGSH has been described in neurons, suggesting that the transport of protons back into the matrix by UCP2 may favor the movement of GSH ( MITOCHONDRIAL MEMBRANE PROPERTIES AND IMPACT ON GLUTATHIONE IMPORT Previous studies in liver mitochondria have revealed that membrane dynamics regulate the transport of mGSH