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For example, a selective pro-apoptotic Bcl-2 inhibitor Venetoclax has been approved for the treatment of chronic lymphocytic and acute myeloid leukemia [74]

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Its tri-agonist receptor profile enables researchers to examine receptor pharmacology, metabolic regulation, lipid metabolism, and cross-tissue signaling networks within controlled laboratory and clinical research environments [1][5]

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Mendes FR, dos Santos Costa C, Wiltenburg VD, Morales-Lima G, Fernandes JAB, Filev R

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