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The Role of B12 in Metabolism Vitamin B12 helps convert fat and protein into energy, supporting healthy metabolic function

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Succinyl-CoA Synthetase, SCS (succinate-CoA ligase, succinate thiokinase): The conversion of succinyl-CoA to succinate, by succinyl-CoA synthetase (SCS), involves the use of the high-energy thioester of succinyl-CoA to drive synthesis of a high-energy nucleotide phosphate (GTP)

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In a subanalysis of SURPASS-3, tirzepatide 10 and 15 mg resulted also in a relative reduction in liver fat content by 4047% compared to 11% with insulin glargine at 52 weeks [44]

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Neurosci Lett 254:2932

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It works by mimicking the action of a natural hormone called glucagon-like peptide-1 (GLP-1)

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