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The flow was generated by a pump reproducing pulsatile pressure patterns (Cucullo et al., in vivo , including a low permeability, TEER values 10 times higher than in transwells, and an enhanced expression of pump molecules

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4 However, its striking success has not led us to a deeper mechanistic understanding of exactly how a protein sequence folds, thus not assisting in the folding of a protein from its sequence

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Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with metabolic syndrome