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According to FDA-approved prescribing information and large-scale clinical trials, there is no established causal link between these medications and blood clot formation

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Although a small number of randomized trials investigating metformin use in patients with CRC are ongoing, these are in unselected populations and may also include other interventions (such as aspirin and physical activity)

Use within 7 to 14 days

With this method, the widening of the artery in response to elevations in blood flow-induced shear stress was evaluated

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