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In summary, this study identifies Ssu72 phosphatase as a new regulator of white adipocyte differentiation and lipid accumulation, which are essential for WAT expansion during HFD-induced obesity

To characterize compound engagement of TGR in adult worms ex vivo, the GSH/GSSG ratio was measured for compounds in Table 1

Furthermore, insulin resistance can lead to abnormal lipid profiles, like low-HDL and high triglyceride (TG) levels

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