This result may be due to the low percentage of functional thyroid tissue in children with cretinism in which T4 is converted to active T3 at the periphery in the presence of Se supplementation only
Memorial Sloan-Kettering Cancer Center Annual Report, 2005
Artesunate is a clinically well-tolerated compound that acts synergistically with sorafenib to induce ferroptosis in the HCC cell lines Huh7, SNU-449, and SNU-182 (97)
For example, encapsulating the adjuvant monophosphoryl lipid A in the core of poly(D, L-lactide-co-glycolide) nanoparticles and then modifying the surface with the tumor-targeting peptide TMTP1 and the DC receptor mannose to form the nanovaccine NP-TP1@MM can capture and enrich more tumor-specific antigens after chemotherapy, stimulate DCs maturation and activate adaptive immunity (103)
Activation of wound healing and tissue repair signaling
For instance, estrogen may interfere with the cross-linking process, leading to a reduction in the mechanical integrity of collagen fibrils
