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In addition, the leptin-receptor-expressing (LepR) neural activity in the dorsomedial hypothalamus (DMH), which sends GABAergic inhibitory inputs to ARC AgRP neurons, is also known to be rapidly increased by sensory detection, the taste of food, or food cues [48,53,54]

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This has been reinforced by anti-addiction findings for GLP-1s

Compounded GLP-1 medications are custom-made formulations available when the brand-name medication is in short supply or when the patient needs a custom dose or formulation that is not commercially available

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