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It promotes NRF2 ubiquitination through the Keap1/NRF2/ARE signaling pathway, induces ROS accumulation, and inhibits the phosphorylation of AktSer473 and mTORSer2448

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After 18 weeks, the authors discovered that the antioxidants in the fruit turned on antioxidant defense pathways, which ultimately increased the activity of genes that boost the production of glutathione