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MK-677 (Ibutamoren) MK-677 (ibutamoren) is an orally active, non-peptide small molecule agonist of the ghrelin receptor (GHSR-1a) that stimulates endogenous growth hormone and IGF-1 secretion, studied in randomized trials in older adults, obesity, and sleep research

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[DOI] [PubMed] [Google Scholar] 74.Shigeto M., Cha C.Y., Rorsman P., Kaku K