However, variant interpretation is complicated by factors such as membrane targeting: for instance, a serine mutation at one of the other Na + -binding residues, N210, causes a reduction in uptake, but also shows mixed localisation, 11 which may itself contribute to disease
If the automated monitoring system records a "failure" (e.g., a conductivity spike or a drop in loop velocity), this constitutes a CGMP record
Pannala, R., Basu, A., Petersen, G
Cell Metab 25(2):262284 Puchalska P, Crawford PA (2021) Metabolic and signaling roles of ketone bodies in health and disease
Saudi J Gastroenterol
Common reasons for rejection include treatment duration restrictions, quantity limits per month, or requirements to try other medications first