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331 ADAMTS5 is closely related to cartilage damage and inflammation

Hills AP, Misra A, Gill JMR, Byrne NM, Soares MJ, Ramachandran A, et al

Once generic versions are approved by local regulatory authorities, they can capture a substantial market share, estimated at 50% to 70% in the first year of commercialisation

Chen S, Yin L, Xu Z, An FM, Liu AR, Wang Y, et al

[2] [3] Patients should be aware of red flags such as severe, persistent abdominal pain (with or without vomiting) which requires urgent assessment due to the small but increased risk of pancreatitis or gallbladder disease associated with these medications