GLP-1 medications are typically administered once weekly via a subcutaneous injection, meaning a small injection just beneath the skin that causes minimal discomfort compared to intramuscular injections
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Digestive side effects of GLP-1s include nausea, bloating, vomiting, constipation, diarrhea, belching, indigestion and more, outlined in Figure 3 of this article and Table 2 of this article
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95% CI 1.05 to 1.44), with longer treatment periods associated with a greater risk [90]