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Oxidative Stress in Obesity Both experimental and clinical studies have shown that obesity and OS are strongly interconnected, despite being difficult to define the temporal sequence of their association (122)

R., Ding, Y., Coletta, C., Mrazek, A

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By triggering ferroptosis in bone-forming and orchestrating cells while simultaneously promoting bone resorption, this axis provides a plausible cellular mechanism for accelerated skeletal fragility