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Furthermore, oxidative stress impairs the antioxidant defense system by decreasing expression of key enzymes such as GSH, catalase, superoxide dismutase and GPX, thus accelerating ferroptosis (56,57)

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The ratio [GSH]/[GSSG] is thought to be around 100 for cells that are not under oxidative stress [41], and [GSH]/[GSSG] = 107.5 in our model cell

Researchers concluded that NAC supplementation can contribute to the maintenance of good health and quality of life in postmenopausal women by decreasing the probability of immune system-related diseases (such as infection) as they age

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Immunity 39 (5), 976985