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In the present study, the IMPHY000797 compound was docked with a hydrolase enzyme (Human SIRT3 bound to Ac-ACS peptide and Carba-NAD), PDB ID:4FVT, with the 2.47

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doi: 10.1093/rheumatology/kes113

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Large-scale CRISPR screens have been applied to study gene function in a wide variety of living systems, including mammalian cells, 12 bacteria, 13 and apicomplexan parasites