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Choline may play a role in supporting the conversion of fat into energy and aid in muscle recovery, helping physical performance

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Long-term administration in mice inhibited development of leukemia by 6-fold and reduced total spontaneous tumor incidence, with no increase in cancer risk despite telomerase activationaddressing theoretical concerns about uncontrolled proliferation

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Drink fluids consistently throughout the day

Final Outlier Calculation for CY 2026 Consistent with historical practice, we used updated data for this final rule with comment period for outlier calculations