Kanurus expertise, Wellstar Cardiologist Dr
Front Plant Sci 8:64 Yoshida H, Tanimoto E, Hirai T, Miyanoiri Y, Mitani R, Kawamura M et al (2018) Evolution and diversification of the plant gibberellin receptor GID1
RA is an immune disorder that causes joint inflammation and damage
Melena causes Upper gastrointestinal tract causes may include: peptic ulcers cancer a Mallory Weiss tear, which is a split in the esophageal inner lining gastroesophageal reflux disease (GERD), which involves the frequent backward flow of acid from the stomach into the esophagus, which can result in ulcers and bleeding cirrhosis, which is severe scarring of the liver varices Additionally, melena may stem from blood disorders presenting as excessive bleeding, such as hemophilia
Several mechanisms could theoretically explain respiratory symptoms in patients taking Mounjaro , though none are definitively established: Gastro-oesophageal reflux disease (GORD) : The delayed gastric emptying caused by tirzepatide (noted in the SmPC) may theoretically exacerbate reflux symptoms in susceptible individuals, potentially leading to chronic cough through aspiration or irritation of the airways [1] Allergic or hypersensitivity reactions : Though uncommon, any medication can potentially trigger allergic responses, which may include respiratory manifestations Coincidental respiratory infections : Patients may develop upper respiratory tract infections unrelated to their diabetes medication It is crucial to consider alternative explanations for cough in patients taking Mounjaro
The actions of GLP-1 include incretin and satiety effects that are mediated via GLP-1 receptors (GLP-1R) in pancreatic islets and metabolic control centers in the hypothalamus 14,15
