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Studies consistently show that weight regain occurs when either medication is discontinued

Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2006) 102:20416

The drug has established a strong therapeutic foundation with semaglutide 2.4 mg approved for chronic weight management in adults with obesity or overweight, with a label expansion in March 2024 adding cardiovascular risk reduction indications

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These also benefit from the economy of scale in terms of manufacturing costs