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An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy

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TB-500 is a synthetic version or fragment associated with thymosin beta-4, a peptide involved in cell migration, tissue remodeling, and repair-related processes

It is produced by the liver and is involved in several biological functions

Critical challenges included insufficient sample size reducing statistical power, reliance on self-reported exposure data introducing recall bias, and inadequate control for confounding factors such as smoking and alcohol consumption

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