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Because these are prescription medications, a licensed provider must prescribe and monitor them

A combination of aerobic exercises (such as walking, swimming, or cycling) and strength training can help enhance weight loss efforts and improve overall fitness levels

MTX clearance is PH dependent, and this lifesaving fact is used to treat its increased plasma concentrations via urine alkalinization [74]

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Underexploration, as defined here, therefore reflects historical and technological context rather than intrinsic therapeutic inadequacy