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Suppositories provide very similar results to IV methods of administration since the ingredients in the suppository are absorbed by the wall of the rectum and carried straight into the systemic circulation (circumventing the entero-hepatic portal system where ingredients are broken down)

[] Intravenous glutamine can reduce lipid peroxidase production and increase tight junction gene expression in kidney cell walls to reduce macrophage-neutrophil infiltration and inflammation pathways

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3 This strongly indicates that continuous treatment is necessary to maintain the benefits

Assuming the best case (synergy) rather than the neutral or worst case is an act of marketing optimism, not science