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Important precautions include: GLP-1 receptor agonists should not be used in patients with type 1 diabetes or diabetic ketoacidosis Caution is advised in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 These medications are not recommended in severe gastrointestinal disease They should not be used during pregnancy or breastfeeding, and semaglutide should be discontinued at least 2 months before a planned pregnancy [1] [7] Your GP or specialist will assess your individual circumstances to determine suitability

MANF: an emerging therapeutic target for metabolic diseases

Understanding semaglutide-related fatigue and whether tirzepatide causes tiredness helps people plan their titration around work and life demands

According to 2024 multi-society guidelines, many patients can continue these medications perioperatively with individualized risk assessment

Congenital melanotic macules have been described, occurring primarily in the tongue

Ipamorelin is a type of peptide that stimulates the production and secretion of endogenous GH