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Weter., 21 (2): 249-255
doi: 10.2353/ajpath.2010.091253
Factors That Can Reduce Glutathione Levels Several lifestyle and environmental factors can deplete glutathione levels , leading to an increased risk of oxidative stress and reduced detoxification capabilities: 1
Lancet (2017) 389(10080):174155
In mice with acute lymphocytic choriomeningitis virus, CD4+ T cells with the silence of mechanistic target of rapamycin complex-2 (mTORC2) impede the formation and growth of memory CD4+ T cells, which is attributed to the IL-7-activated mTORC2AKTGSK3 signaling pathway, leading to excessive GPX4 peroxidase and suppression of ferroptosis in memory cells (98)
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