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It arises due to a combination of genetic and lifestyle factors that contribute to defective production of insulin from pancreatic beta cells, and/or resistance to its uptake by insulin receptors located in peripheral and central tissues in the body

Youre comfortable with potentially slightly higher side effect rates for better results

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A recent cross-sectional study involving 124 participants indicated that 56% of patients still exhibited elevated residual gastric contents despite halting incretin agonists for a minimum of 7 days, thus challenging the practice of discontinuing long-acting GLP-1 RAs solely for this duration prior to surgery [19]

Do not reduce frequency while you are actively trying to lose weight